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House, also known as House, M.D., is an American television medical drama that debuted on the Fox network on November 16, 2004. The program was co-created by David Shore and Paul Attanasio; Fox officially credits Shore as creator. The show's central character is Dr. Gregory House (Hugh Laurie), an unconventional, maverick medical genius who heads a team of diagnosticians at the fictional Princeton‑Plainsboro Teaching Hospital (PPTH) in New Jersey. The character has similarities to Sherlock Holmes: both are forensic geniuses, musicians, drug users, aloof, and largely friendless. The show's premise originated with Attanasio, while Shore was primarily responsible for the conception of the title character. The show's executive producers include Shore, Attanasio, Attanasio's business partner Katie Jacobs, and film director Bryan Singer. It is largely filmed in Century City.

Dr. House often clashes with his boss, hospital administrator and Dean of Medicine Dr. Lisa Cuddy (Lisa Edelstein), and his diagnostic team, because many of his hypotheses about patients' illnesses are based on subtle or controversial insights. House's only true friend is Dr. James Wilson (Robert Sean Leonard), head of the Department of Oncology. During the first three seasons, House's diagnostic team consists of Dr. Robert Chase (Jesse Spencer), Dr. Allison Cameron (Jennifer Morrison), and Dr. Eric Foreman (Omar Epps). At the end of the third season, this team disbands. Rejoined by Foreman, House gradually selects three new team members: Dr. Remy "Thirteen" Hadley (Olivia Wilde), Dr. Chris Taub (Peter Jacobson), and Dr. Lawrence Kutner (Kal Penn); the latter was written out of the series toward the end of season 5. Chase and Cameron continue to appear in different roles at the hospital until early in season 6. Cameron then leaves the show, and Chase returns to the diagnostic team.

House is critically acclaimed and has high viewership ratings. It was among the top ten rated shows in the United States from its second through its fourth season; in the 2008–09 season, it fell to nineteenth overall. Distributed to 66 countries, House was the most watched television program in the world in 2008. The show has received several awards, including a People's Choice Award, a Peabody Award, two Golden Globe Awards, and three Primetime Emmy Awards.

As an infectious disease specialist, Dr. Gregory House (Hugh Laurie) is a brilliant diagnostician who loves the challenges of the medical puzzles he must solve in order to save lives. House solves the inexplicable cases that other doctors cannot understand.

House isn't alone in this quest. His team includes neurologist Dr. Eric Foreman (Omar Epps), a neurologist with a troubled youth and a desire to avoid becoming as abrasive as House; immunologist Dr. Allison Cameron (Jennifer Morrison) - who sometimes cares too much and has conflicting feelings about House; and Dr. Robert Chase (Jesse Spencer), a specialist in intensive care who has lived a very privileged life. House's good (and possibly only) friend Dr. James Wilson (Robert Sean Leonard) is an oncology specialist, who has to help and stand up for House on a regular basis, while trying to get him to face a few harsh truths.

House must also deal with his boss, Lisa Cuddy (Lisa Edelstein) who, while often opposing House's unconventional methods, must admit that he is the best doctor on her staff. When a patient’s life hangs in the balance, House will do anything, including breaking the law, taking risks other doctors would not take, and sometimes even going as far as actually interacting with a patient. House’s methods may be controversial but his results speak for themselves.

Inconsistencies with his team forced House to hire a new batch of doctors. This year House used an elimination process and the end resulted in hiring, Dr. Lawrence Kutner (Kal Penn), Dr. Remy Hadley (Olivia Wilde), and Dr. Christopher Taub (Peter Jacobson). Although his old team no longer takes orders from House they're still around to throw in their professional knowledge when need is dire. Together they will continue to solve cases most doctors can't.

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